Téléchargez le livre : NMR-Bioassay Guided Isolation of the Natural 20S Proteasome Inhibitors from Photorhabdus Luminescens

NMR-Bioassay Guided Isolation of the Natural 20S Proteasome Inhibitors from Photorhabdus Luminescens

A Novel NMR-Tool for Natural Product Detection
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Éditeur :

Springer

Collection : Springer Theses

Paru le : 2014-06-23

Martin Stein's thesis describes a novel methodology for natural product discovery. Due to its high degree of reproducibility, robustness and sensitivity, the technique can be utilized to detect even trace amounts of bioactive substances in heterogeneous matrices such as fermentation broths or crude ...
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Description du livre

Martin Stein's thesis describes a novel methodology for natural product discovery. Due to its high degree of reproducibility, robustness and sensitivity, the technique can be utilized to detect even trace amounts of bioactive substances in heterogeneous matrices such as fermentation broths or crude organic extracts. This research is thus relevant for a large number of researchers working in natural product discovery. Applications of this novel NMR-based approach include suitable environmental triggers for the induction of biosynthetic machineries. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens. This thesis has led to a number of publications in high-impact journals.

À propos

Auteur
Martin Lorenz Stein
Éditeur
Springer
Collection
Springer Theses
Parution
2014-06-23
Pages
71 pages
EAN papier
9783319079134

Auteur(s) du livre


Defaut-Illustration Martin Lorenz Stein

Caractéristiques détaillées - droits

EAN EPUB
9783319079141
Prix
52,74 €
Nombre pages copiables
0
Nombre pages imprimables
7
Taille du fichier
1137 Ko
Ce livre est accessible aux handicaps informations d'accessibilité

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